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Architects of Aesthetics

Regenerative aesthetics, reimagined from within
Aging, injury and significant weight loss can change the quality of soft tissue over time. As fat and the extracellular matrix are depleted or disrupted, the tissue environment may lose the structure, volume and regenerative conditions that help support natural form.
This is the unmet need CXU™  is being designed to address.

Beyond volume alone

Conexeu is developing CXU™, an injectable bioregenerative extracellular matrix platform designed to support the restoration of soft tissue structure, function and form.
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Many established aesthetic injectables primarily reduce muscle activity, add volume or stimulate collagenproduction; CXU is being developed around a different scaffold-based hypothesis.

The opportunity is not only to restore form, but to explore whether structural scaffolding can support the biology associated with tissue remodeling.

One core platform, designed around form, structure and tissue biology.
Designed to Flow

At room temperature, CXU flows as a liquid, allowing for placement into the tissue with a fine-gauge needle.
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Its flow characteristics are designed to support controlled injectable placement within the treatment area.

Support the biology that makes remodeling possible
Designed to Transition

At body temperature, CXU transitions into a gel, allowing for stability that may provide immediate volume.

Over time, CXU may provide structural support as tissue integration, remodeling and regeneration occur.

Understanding bioregeneration in aesthetics

Bioregeneration is an emerging area of aesthetic science focused on supporting the body’s ability to restore tissue structure and function over time.

While many traditional aesthetic treatments focus on muscle activity, volume or collagen stimulation, bioregenerative approaches explore the biology of repair and remodeling.

For Conexeu, this means designing materials that may help create the right environment for new tissue development, while gradually resorbing as the body remodels.

Why it matters for the category

As the field of aesthetics continues to evolve, patients and providers are increasingly looking for outcomes that appear natural, integrate with the body and support long-term tissue quality.

Bioregeneration may represent an important next step in that evolution. The goal is not simply to fill space, but to support tissue restoration.

CAUTION: CXU™ is a medical device candidate in preclinical development and is not cleared or approved for marketing in the United States or any other jurisdiction.

How CXU Works

How it works

CXU is designed as a flowable collagen-ECM scaffold intended to conform to soft-tissue spaces and support host-tissue interaction and remodeling.9,3,6

Flow

Designed to:

  • Allow for precise injectable placement
  • Conform to varied soft tissue environments
  • Provide immediate volumizing support at the placement site
Integrate

Designed to:

  • Form a collagen-ECM scaffold intended to support tissue ingrowth
  • Support population of the scaffold by the body's own cells
  • Support integration with the surrounding tissue environment
Regenerate

Designed to:

  • Be gradually resorbed over time
  • Support the body's natural regenerative processes
  • Support retention of the body's own tissue at the placement site
CAUTION: CXU™ is a medical device candidate in preclinical development and is not cleared or approved for marketing in the United States or any other jurisdiction.
*Data on File. Conexeu. 2026. Preclinical findings; not peer-reviewed. Clinical.

Key Features

When tissue quality changes due to age, environmental exposure, or significant weight loss, CXU™ is designed to help create the conditions for soft tissue restoration.*

Immediate structural support

Designed to provide structural and volumizing support at the time of placement. 1,5,7,9,12

Host tissue integration

Designed to support cellular ingrowth and remodeling.3,9,10,12

Gradual resorption

Designed to resorb over time in support of host tissue remodeling.12

Injectable delivery

Being developed as an injectable, non-surgical approach to soft-tissue augmentation.1,5,9,10,12

Biocompatibility

Designed to be biocompatible and to minimize inflammatory response.10,12

*Design intent reflects preclinical development in laboratory and animal models. Animal physiology differs from human physiology. Clinical safety and effectiveness in humans have not been established.

Explore Other Applications

IMPORTANT NOTICES: CXU™ is a medical device candidate in preclinical development. It has not been submitted to or reviewed by the U.S. Food and Drug Administration. Safety and effectiveness have not been established. See Forward-Looking Cautionary Statement.Terms such as 'next-generation,' 'advanced,' 'innovative,' and 'bioregenerative' reflect the Company's assessment of its technology relative to existing approaches and are not intended as representations of regulatory status, clinical performance, or guaranteed commercial outcomes. CXU™ is an investigational medical device candidate. Safety and effectiveness have not been established. See Forward-Looking Cautionary Statement.
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