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Architects of Ten-Minute Tissue™

Designed to fill deep wounds, not just sit on top.
A serious burn, injury or surgery can take away more than skin. It can destroy the natural framework underneath, which is the structure the body rebuilds on. Ten-Minute Tissue™ is an investigational device being developed for these wounds. The unique formula starts as a liquid, designed to fill every contour of the wound. In about ten minutes, it sets into a cohesive, tissue-like structure.
Conexeu is committed to helping improve outcomes for people living with serious injuries, including burns.

Overview

Every tissue in the body is supported by a natural framework called the extracellular matrix, or ECM. Like scaffolding, the ECM gives cells a structure to organize around.

Ten-Minute Tissue™ is built on the CXU™ platform, a collagen-based scaffold designed to resemble this natural framework.

The name reflects how it works. Applied as a liquid, Ten-Minute Tissue™ can conform to deep and irregular wound spaces that a flat dressing may not reach. At body temperature, the liquid sets into a cohesive, three-dimensional structure in about ten minutes.Once formed, it is designed to remain in place and provide a framework for the body’s natural repair process.

CAUTION: Ten-Minute Tissue™, built on the CXU™ platform, is a medical device candidate in preclinical development and is not cleared or approved for marketing in the United States or any other jurisdiction.

How Ten-Minute Tissue™ Works

How it works

It starts as a liquid and transforms into a tissue-like structure.9,3,6

Liquid
  • Goes on as a liquid
  • Flows into deep and uneven spaces
  • Follows the shape of the wound
Ten Minutes
  • Gels near body temperature
  • Forms in about ten minutes
  • Designed to stay in place once set
Tissue-Like
  • Designed to resemble the body’s natural framework
  • Intended to support the body’s own tissue repair
CAUTION: Ten-Minute Tissue™, built on the CXU™ platform, is a medical device candidate in preclinical development and is not cleared or approved for marketing in the United States or any other jurisdiction.

Key Features

What Ten-Minute Tissue™ is designed to bring to deep wounds from burns, injury or surgery.*

Modeled on the Body

A single thermosensitive, flowable ECM scaffold using the body's natural building blocks.

Shaped to the Wound

Because it starts as a liquid, it is designed to fill the whole wound, including deep and irregular spaces, not just the surface.

Stays in Place

Once set, it is designed to hold its position as one cohesive structure, giving the body’s own repair process a stable framework to build on.

*Design intent based on preclinical evidence. These findings were generated in controlled laboratory settings and animal models. Animal physiology differs from human physiology and these findings may not be predictive of clinical performance or safety in humans. Clinical significance not yet established.

The Language

of Ten-Minute Tissue™

Key Terminology

Ten-Minute Tissue™

Conexeu’s device candidate for deep wounds from burns, injury or surgery. It goes on as a liquid and is designed to transform into a tissue-like structure in about ten minutes.

CXU™ platform

Conexeu’s collagen-based scaffold: a supportive framework made with collagen, a protein that helps give skin its strength. Ten-Minute Tissue™ is built on it.

Investigational device

A medical device still in development and testing. Ten-Minute Tissue™ is in preclinical (laboratory and animal) studies, has not been cleared or approved by the FDA and is not available for sale.

Flowable

Able to pour and spread like a liquid, so Ten-Minute Tissue™ is designed to reach into deep, uneven spaces and take the shape of the wound.

Thermosensitive

Responsive to temperature. Ten-Minute Tissue™ is designed so that the body’s warmth triggers its change from a liquid into a gel.

Setting (gelation)

The change from liquid to a gel that holds together in one piece. Ten-Minute Tissue™ is designed to set in about ten minutes and then stay in place.

Tissue-like structure

A structure designed to resemble the natural tissue framework that the body’s tissue is built on. Ten-Minute Tissue™ is a material, not living tissue.

Natural tissue repair

The body’s own process of fixing damaged tissue is, as cells move into an injury and gradually rebuild it. Ten-Minute Tissue™ is intended to support this process by providing the missing scaffold, not replace it.

Explore Other Applications

IMPORTANT NOTICES: CXU™ is a medical device candidate in preclinical development. It has not been submitted to or reviewed by the U.S. Food and Drug Administration. Safety and effectiveness have not been established. See Forward-Looking Cautionary Statement.Terms such as 'next-generation,' 'advanced,' 'innovative,' and 'bioregenerative' reflect the Company's assessment of its technology relative to existing approaches and are not intended as representations of regulatory status, clinical performance, or guaranteed commercial outcomes. CXU™ is an investigational medical device candidate. Safety and effectiveness have not been established. See Forward-Looking Cautionary Statement.
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