Oral Health

Architects of Oral Health

Designed to lay the structural foundation for healthy gum tissue.

In oral health, aging, bacteria, chronic tissue stress or trauma can degrade or destroy the periodontal extracellular matrix (ECM) and compromise the biological foundation attachment depends on. When that scaffold is lost, healing becomes disorganized tissue repair and not regeneration. Yet many current approaches still focus on coverage rather than restoring the structural foundation needed for organized tissue regeneration.

This is the unmet need CXU is poised to address.

OVERVIEW HOW IT WORKS KEY FEATURES

Architects of Oral Health

Overview

Engineered to mimic the body’s natural extracellular matrix, our collagen-based ECM is designed to create a more complete structural environment than collagen alone. In oral care, CXU is being developed to help rebuild the soft-tissue architecture needed for healthy attachment, organized healing and regeneration. Designed to gel in place within approximately 10 minutes, it conforms naturally to the treatment site, fills irregular spaces and potentially supports cell infiltration and vascular ingrowth across periodontal and implant procedures.

CAUTION: CXU™ is a medical device candidate in preclinical development and is not cleared or approved for marketing in the United States or any other jurisdiction.

How CXU Works

How it works*

The CXU formula creates a permissive and adaptive extracellular matrix environment, designed to conform, integrate and regenerate.^9,3,6

Conform

Flows into irregular spaces
Maintains close tissue contact
Adapts to local tissue architecture

Integrate

Gels near body temperature
Forms within approximately 10 minutes
Stays in place without migration

Regenerate

Designed to mimic natural tissue ECM, to support durable closure and tissue regeneration with reduced scarring

CAUTION: CXU™ is a medical device candidate in preclinical development and is not cleared or approved for marketing in the United States or any other jurisdiction.

Key Features

When tissue is destroyed by trauma, aging, or exposure to certain bacteria CXU is designed to provide these benefits.*

Collagen-ECM Scaffold

Designed to more closely mimic the complexity of the body’s natural extracellular matrix, offering a more complete structurally supportive environment than collagen alone.

Graft-Free Tissue Support

Designed to support soft tissue restoration by providing an cohesive injectable ECM scaffold potentially reducing reliance on autologous tissue harvest.^{†* [*3][*9][*10]}

Better Outcomes

Designed to support organized soft tissue closure with a reduced inflammatory profile, consistent with improved repair outcomes inpreclinical models.

*Design intent based on preclinical evidence. These findings may not be predictive of clinical performance or safety. Clinical significance not yet established.

IMPORTANT NOTICES: CXU™ is a medical device candidate in preclinical development. It has not been submitted to or reviewed by the U.S. Food and Drug Administration. Safety and effectiveness have not been established. See Forward-Looking Cautionary Statement.Terms such as 'next-generation,' 'advanced,' 'innovative,' and 'bioregenerative' reflect the Company's assessment of its technology relative to existing approaches and are not intended as representations of regulatory status, clinical performance, or guaranteed commercial outcomes. CXU™ is an investigational medical device candidate. Safety and effectiveness have not been established. See Forward-Looking Cautionary Statement.

Architects of Oral Health

Overview

How it works*

Key Features

Explore Other Applications

Wound Care

Aesthetics

Oral Health

Animal Health

3-D Tissue

Contact Us

OUR PLATFORM | APPLICATIONS

Architects of Oral Health

Overview

How it works*

Key Features

Explore Other Applications

Wound Care

Aesthetics

Oral Health

Animal Health

3-D Tissue

Contact Us

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